Researchers have successfully identified biological signatures in pediatric patients with newly diagnosed Crohn’s disease (CD) capable of predicting whether a child will develop disease-related complications requiring major surgery within three to five years. The results of this research, “Prediction of complicated disease course for children newly diagnosed with Crohn’s disease: a multicentre inception cohort study,” have been published in the journal, The Lancet.
This groundbreaking work is the result of the Crohn’s & Colitis Foundation’s “RISK Stratification” study, the largest new-onset study completed on pediatric Crohn’s disease patients. It is a multicenter research initiative that consists of 25 U.S. institutions and three from Canada and a cohort of 1,112 CD children enrolled at diagnosis, of which 913 were included in the published study. Of the 28 research sites, four are loc