Kristen
Donahue
M.S. Bioinformatics Student
School of Biological Sciences
I am Kristen Donahue, an M.S. Bioinformatics student at Georgia Tech working with Dr. Yuhong Fan to study single-cell transcriptomics and chromatin biology. My research focuses on understanding how linker histone H1 regulates embryonic development through computational analysis of SPLiT-seq data. I am experienced in developing scRNA-seq pipelines for embryonic gene network analysis using Python, R, and bioinformatics tools (Seurat, DESeq2, STAR, Trimmomatic, Slingshot, UMAP), and HPC workflows to process large datasets.
Outside of my research I have applied data science methods during my performance analytics internship at OldCastle APG, where I developed predictive models and interactive Tableau dashboards. I hope to expand my research into advanced differential expression analysis as well as explore opportunities for data science applications.
- Single-cell transcriptomics
- Epigenetics and chromatin biology
- Gene regulatory network analysis
- Machine learning in biomedical data analysis